How to cite us:

Iserte JA, Simonetti FL, Zea DJ, Teppa E, Buslje CM.
I-COMS: Interprotein-COrrelated Mutations Server.
Nucleic Acids Res., vol. 43, issue. W1, pp. w320-325, Jul 2015.


Useful publications for understading how i-COMS works

  1. Buslje CM, Santos J, Delfino JM, Nielsen M. "Correction for phylogeny, small number of observations and data redundancy improves the identification of coevolving amino acid pairs using mutual information." Bioinformatics (Oxford, England), vol. 25, no. 9, pp. 1125-31, May 2009.

  2. Marks DS, Colwell LJ, Sheridan R, Hopf TA, Pagnani A, Zecchina R, Sander C. "Protein 3D Structure Computed from Evolutionary Sequence Variation." PLoS ONE 2011, 6:e28766.

  3. Jones DT, Buchan DWA, Cozzetto D, Pontil M "PSICOV: precise structural contact prediction using sparse inverse covariance estimation on large multiple sequence alignments." Bioinformatics 2012, 28:184-190.

  4. Kajan L, Hopf T, Kalas M, Marks D, Rost B "FreeContact: fast and free software for protein contact prediction from residue co-evolution." BMC Bioinformatics 2014, 15:85.

Bioinformatics Unit

Leloir Institute Foundation